0.5mg of Semaglutide from a 12mg vial in 3.5mL: how many units?

Answer

Draw 14.6 units on a U-100 insulin syringe. A 12 mg Semaglutide vial reconstituted with 3.5 mL of bacteriostatic water is 3.43 mg/mL, so 0.5 mg is 0.146 mL. That vial holds about 24 doses at this strength.

This page also answers

  • How many units is 0.5mg of sema?
  • 0.5mg sema on a U-100 syringe
  • What do I draw for 0.5mg if I used 3.5ml?
  • 0.5 mg sema in units

Your draw

Vial 12 mg
Bacteriostatic water 3.5 mL
Concentration 3.43 mg/mL
Dose 0.5 mg
Volume to draw 0.146 mL
U-100 syringe 14.6 units
U-40 syringe 5.8 units
Doses per vial 24

Dose chart: 12 mg vial in 3.5 mL

DoseVolumeU-100 unitsU-40 unitsDoses per vial
0.125 mg 0.036 mL 3.6 1.5 96
0.25 mg 0.073 mL 7.3 2.9 48
0.5 mg 0.146 mL 14.6 5.8 24
1 mg 0.292 mL 29.2 11.7 12
1.7 mg 0.496 mL 49.6 19.8 7
2 mg 0.583 mL 58.3 23.3 6
2.4 mg 0.7 mL 70 28 5
3 mg 0.875 mL 87.5 35 4

Doses that would need more than a full 1 mL syringe are omitted. Use less bacteriostatic water for those.

Common questions

What if I used a different amount of water?
Then the unit number changes. Units depend on concentration, not just dose. Run your actual vial size and water volume through the reconstitution calculator rather than copying a number from a chart that assumes 3.5 mL.
Is that on a U-100 or U-40 syringe?
14.6 units is the U-100 reading, the standard insulin syringe at 100 units to 1 mL. On a U-40 syringe the same 0.146 mL reads 5.8 units.
How many 0.5 mg doses will this vial give?
About 24 doses from a 12 mg vial. Reconstitution volume doesn't change that. It only changes how many units you draw each time.
How long is it good for after mixing?
Refrigerate reconstituted peptide at 36–46°F (2–8°C). Most references give 28–60 days once mixed, depending on the preservative in the bacteriostatic water. Do not freeze it, and inspect for cloudiness or particles before every draw.

Run your own numbers

These figures assume the vial and water volumes named above. Change either one and the units change with it.